Who says you need to splash millions like Bryan Johnson eh?
A group of researchers investigated the influence of two dietary supplements and physical activity on biomarkers used to assess biological aging.
The researchers have now disclosed the findings of their investigation, which explored how the use of certain supplements might assist in decelerating the aging process.
The objectives
The research was released last month in Nature – titled Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial.
The study asserts: “The aim of our analysis was to evaluate the hypothesis that vitamin D supplementation, omega-3 supplementation and a simple home exercise program (SHEP), both separately and together, would hinder biological aging in a larger clinical trial.”
An initial trial – DO-HEALTH – included 2,157 participants and demonstrated that the introduction of ‘omega-3 alone’ contributed to a 13 percent reduction in the frequency of infections and a 10 percent decline in the incidence of falls.
Do you take supplements? (Getty Stock Images)
The combination of omega-3, vitamin D, and exercise, all three offered a notable ‘additive advantage on decreasing prefrailty by 39 percent and incident invasive cancer by 61 percent over a three-year follow-up’.
A total of 777 participants were subsequently drawn from this trial and utilized for the study focusing on longevity.
The study
The DO-HEALTH Bio-Age trial incorporated 777 of the 2,157 DO-HEALTH participants with DNAm measures at baseline and after three years’ and ‘enrolled 2,157 generally healthy and active adults aged 70 years and older across five countries in Europe’.
The study examined the impacts of administering 2,000 IU of vitamin D per day alongside one gram of omega-3 daily while engaging in a simple home exercise program ‘three times 30 minutes per week’ – ‘individually and together during an intervention duration of three years’.